Searchable abstracts of presentations at key conferences in endocrinology

ea0025p86 | Clinical biochemistry | SFEBES2011

Calcitonin negative medullary thyroid cancer

Woods David , Santhakumar Anjali , Johnson Sara , Aspinall Seb

Medullary thyroid cancers (MTC) account for about 5% of thyroid cancers. The biochemical hallmark of MTC is the secretion of calcitonin (CT). CT levels are both a key feature of pre-operative diagnosis and post-operative follow up. CT screening in a cohort of over 10 000 patients with thyroid nodular disease has demonstrated that a positive CT test has a higher diagnostic sensitivity and specificity for MTC than fine needle aspiration (FNA). They may also secrete carcinoembryo...